Seeing how CO is not a playable word in Scrabble, are there any two-letter words starting with C you can play in Scrabble? Are There Any 2-Letter C-Words for Scrabble? So, you cannot play CO in Scrabble either. However, generally speaking, you cannot use abbreviations in Scrabble. Depending on capitalization and context, “co” could be short for company, commanding officer, Colorado, carbon monoxide, cobalt, care of, county, and more.
It’s true that CO is a common abbreviation.